What Can 40+ Total Do For You?
✔️ Restores Hormone Health
✔️ Promotes Healthy Aging
✔️ Curbs Cravings
✔️ Supports Cellular Energy & Sleep
✔️ Promotes Urinary Health & Immunity
Elevate your holistic health with our all-encompassing support. Experience multi-symptom relief thoughtfully designed, and intentionally paired to help you navigate every phase of your wellness journey.*
What They're Saying
Real Reviews
Ingredients
MEno
Daily
UTI
RED CLOVER EXTRACT
Our meticulous extraction process combining water and alcohol helps retain the valuable active compounds in red clover. Phytoestrogens found in red clover alleviate menopause symptoms, support bone health, and promote overall well-being.
OLIVE FRUIT EXTRACT
Crafted to retain the highest concentration of active antioxidant molecules found in olives, it is rich in powerful antioxidants that enhance skin thickness and moisture and combat aging when exposed to light.
BERGAMOT PHYTOSOME
Extracted to maintain the same potent polyphenol ratio as the natural juice, our bergamot is then encapsulated in a phytosome to enhance absorption. It effectively manages cholesterol, blood lipids, and visceral fat accumulation.
Think of The Daily Hormone Balance like a super-powered multivitamin. You get your daily micronutrients that we are often difficient in as well as the support of Berberine, Passionflower, and Grapeseed that helps calm our mind and body.
Work Better Together
Holistically paired to greatly reduce symptoms like night sweats, hot flashes, mood swings, and risks of UTIs. Stop menopause symptoms from controlling your life.
Real People, Real Clinical Trials
Urinary Tract
100%
UTI-FREE IN 3 MONTHS*
55%
RELIEF IN 12 HOURS*
6.53x
URINARY HEALTH SCORE IMPROVEMENT*
LEARN MORE
Who Is This For?
Healthy Aging
Peri / Menopause
Our science-backed wellness supports hormone balance for total well-being. Hormone fluctuations, whether dipping or surging, can lead to mood swings, cramps, and fatigue. We provide support for sex hormones, metabolic hormones, immune response, and microbiome.
Introducing the 40+ Total Kit, designed to comprehensively address your well-being.
FAQs
How do I take 40+ Total?
Menopause Essentials: Take 1 capsule daily, with food.
The Daily: Take 2 capsules once a day, with food.
Urinary Tract Cleanse: Take one capsule every 12 hours while experiencing discomfort, then continue with one daily for at least 2-3 months as prevention. It can be taken with or without food.
Based on our clinical trial, some participants experienced symptom relief within the first few weeks, with significant improvement typically seen between 2-3 months. However, with all supplements, the more consistently you take them, the more robust results you will see.
Can I take Semaine with other medication?
All of our supplements are thoughtfully designed to work even better together! We are complex humans and that means we need different supplements at different stages of life. However, it's always a good idea to check with your doctor if you are starting any new supplement and already taking 1 or more medications. We have a white paper that you can share with your doctor that explains the formulation, dosage, and clinical trial results so that they can help you make an informed decision: White Papers
Are your supplements FDA-regulated?
Semaine supplements are FDA-regulated, not approved, just like any supplement on the market. However, our supplements are made in an FDA facility and we third-party test all of our products.
What is your happiness policy?
If you are not completely satisfied with your first Semaine purchase, we’re happy to provide a full refund for up to two bottles within 60 days of the original shipping date of your first bottle. Shipping is not refundable. Our support team will be glad to help you with this process. For more information, please read our Customer Happiness Guarantee page in our Help Center.
How do I start a subscription?
Each product page has a subscription or one-time purchase option. If you would like to start a subscription, make sure you click on the "Subscribe and save" option.
Feel Your Best, at the Cellular Level
Works Even Better, Together
40+ PROTECTION
PERI/MENOPAUSE RELIEF + BLADDER SUPPORT
Designed for urinary and kidney protection, and reducing hot flashes, night sweats, and mood swings. Kick menopause symptoms and UTIs to the curb.
40+ ESSENTIALS
CLINICALLY PROVEN
PERI/MENOPAUSE RELIEF
This combo supports hormonal balance, metabolism, and mood. Ditch the pesky symptoms of menopause.
DAILY DEFENSE
BLADDER SUPPORT + HORMONE BALANCE
A dynamic duo that supports metabolic hormones, urinary health, and immunity. Say goodbye to unhappy hormones and UTIs.
PERFECT CYCLE
EASE PMS, BALANCE HORMONES, UTI RELIEF
A trio to support bladder health, mood, cramps, and bloating. Kiss period dread and UTIs goodbye.
Multi-symptom support for tackling hot flashes, mood swings, and night sweats. Formulated with natural ingredients including bergamot phytosome, red clover extract, and olive fruit extract, to go beyond symptom relief, addressing the root causes for long-lasting results.*
All-in-one metabolic support and hormone-balancing supplement. Made with premium ingredients that are clinically proven to improve 15 measures of unbalanced hormones within just 8 weeks; including Berberine Phytosome, Vitamin B Complex, Passionflower, Magnesium, Grapeseed Extract, and Zinc*
Using two powerful plant extracts clinically studied to promote urinary tract health, help stop microbial build-up and support immunity.*